Seaweed, thyroid, hypothyroidism, hyperthyroidism

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Seaweed, thyroid, hypothyroidism, hyperthyroidism

Postby herbsandhelpers » Tue May 18, 2010 8:18 pm

Which Seaweeds Are Best To Eat?

Nori: (several species of the red algal genus Porphyra) is probably the most popular seaweed for eating, both historically and today. It is yummy in soups, re-wetted in salads, just as a dried snack, toasted lightly in a dry iron skillet, deep-fat-fried with cooked rolled oats as the Celtic "Laver Bread", and as a food wrap in sushi. Nori sheets are a manufactured food product. Nori was eaten abundantly by indigenous peoples wherever both occurred. It tends to have a sweet, meaty flavor pleasant to most palates.

Dulse: another red alga, is another easy to eat snack but quite salty and often a little fermented in the marketplace; its relatively high fatty acid content results in rancidity after a year or more in storage.

The large brown"kelps" (Kombu/Laminaria groendlandica, Sugar Kelp/Laminaria saccharina, Wakame/Alaria spp.) can be eaten just dried but usually are easier to eat when cooked with grains, legumes or miso soup broth.

The bright green dried fronds of the local giant kelp, "Bull Kelp"(Nereocystis luetkeana). are a great snack, salty and high in vitamins and minerals (up to 50% dry weight), particularly potassium, protein and free amino acids.

Other brown algae: Hijiki/Cystceria geminata, Sargassum/Sargassum mutica, Sea-palm, are usually best cooked with wet food as in soups, miso broth, grains, legumes, vegetable pies and stews.

Sea Lettuce (Ulva lactuca and Monostroma spp.): has a strong seafood taste and odor but is easy to eat as a snack or in salads since it is quite delicate after drying and crumbles easily into tiny tender pieces.

How Long Do Seaweeds Keep After Harvest?

In proper storage, most totally-dried sea vegetables stay nutritionally and medicinally secure indefinitely. The minerals do not degrade; the phycocolloids slowly fragment over years; the pigments slowly fade, especially the chlorophylls; fats slowly become rancid; proteins fragment slowly to polypeptides and amino acids.

Proper storage ideally means that the sea vegetables are stored in completely air-tight waterproof opaque containers (not paper or plastic bags) at temperatures less than 70 degrees F, in the dark. Do not store dried sea vegetables in a refrigerator or near sources of strong odors. Dried sea vegetables are very odor-absorptive. They also tend to be aggressively hygroscopic, (they absorb water from the air) which is why dry storage is essential. Some sea vegetables such as Nori, improve in taste and texture for at least 20 years in dry storage, becoming sweeter as complex carbohydrates fragment to simple sugars, and meatier as proteins fragment to amino acids.

What Health And Nutritional Benefits Can Result From Regular Seaweed Consumption?

From my perspective, sea vegetables are an essential component of all therapeutic diets. Seaweeds, eaten regularly, are the best natural food sources of biomolecular dietary iodine. Seaweeds do not seem to accumulate fat-soluble pesticides and industrial wastes such as PCP, PCB and dioxin, unlike marine animals; the latter are also good sources of dietary iodine. Land-based vascular plant iodine content tends to be low. No land plants are reliable sources of dietary iodine. Food crops grown on mineral-depleted soils from poor agricultural practice usually contain inadequate amounts of dietary iodine. Iodine is the essential element in most thyroid hormones, natural and synthetic. Iodine is also essential for the maintenance of normal mammary gland architecture and salivary gland health.

A note: What exactly does "eaten regularly" imply?

To me, it means eating 5-15 grams of dried seaweed(s) at least twice a week. An ounce (29 grams) a week is slightly more than three pounds a year. My personal consumption is around 10 pounds a year (4kg). I usually suggest consuming brown seaweeds and red seaweeds in the year at a 2:1 ratio; roughly 2 pounds of brown algae and one pound of red algae. Regular consumption of sea vegetables in the diet encourages resident intestinal microflora to develop sea vegetable digestive enzymes; most of us can so adapt in 4-6 weeks. Prolonged or heavy intermittent antibiotic use can severely reduce a human's seaweed digestive capacity. Just eating sea vegetables is only a beginning; for optimal health effects, one must also digest the sea vegetables and absorb nutrients from them.

EDIBILITY: Which seaweeds are edible?

All seaweeds are edible. Many are unpalatable. Some are very tasty after drying, roasting, or lightly-steamed. Most are not very tasty fresh, wet and alive. Powdered or flaked sea vegetables are often best, gradually introduced dietarily in cooked foods to patients, especially the resistant or reluctant patient. Real powdered kelp (NOT rinsed, de-salinized, reconstituted flakes) is a delicious high-potassium salt replacement in most cooked foods and on popcorn.

Dietary Minerals:

Sea vegetables are excellent sources of most minerals, especially: potassium, sodium, calcium, magnesium, sulfur, nitrogen, iron, zinc, boron, copper, manganese, chromium, selenium, bromine, vanadium, nickel; often better sources than meat, whole milk, or eggs and usually better than any land plants. This means that high-quality sea vegetables can be used to compensate for the frequent low mineral content of food plants and animals grown "factory-style" on mineral-depleted soils. (See: Bergner).

Active Removal Of Radioactive and Heavy Metal Toxic Cations:

The phycocolloids, Algin in all brown algae, and Carageenan and Agar in many red algae, aggressively trap metallic ions. The isolated colloids and/or the seaweeds containing them can be used to remove heavy metals from our food and bodies and carry those metals out in the stool. Although many seaweeds contain some radioactive elements, careful research indicates that these elements are usually not released into our food or bodies. Powdered Kelp(s), algin, even sodium alginate, are effectively used to move radioactive and heavy metals out of the body. The metabolic process is slow and deliberate. The Swedish government first recommended a 5 gm/day dose of powdered Kelp, Algin or sodium alginate as both a detox treatment and a protective treatment against radioactive fallout circa 1954. The United States Atomic Energy Commission did as well in about 1956; this was later rescinded in about 1960, so as not to alarm the public unduly. Unfortunately, we are regularly taking in radioactive isotopes from the total world contamination by continual radioactive fallout from all nuclear power plants, weapons facilities and past nuclear ÍtestsÎ. We are all radioactively hot. We have no choice. All of our food, air, soil, and water is contaminted. Any way we can reduce our total body burden of radioactive isotopes will help our health., by reducing our personal exposure to ionizing radiation from radioactive isotope decay in our respective bodies. (See: S. Schecter and S. Smith). Dietary phycocolloids also bulk and soften the stool, soothe the GI tract, and help relieve chronic constipation. CAUTION: Red seaweeds high in Carageenan can irritate the inner bowel lining in patients with Irritable Bowel Syndrome, CrohnÌs disease, or ulcerative colitis, probably by local lining astringency water extraction.

Vitamins:

Most sea vegetables are excellent sources of the known vitamins (A, B's, especially B12, C, D, E, and K) as well as essential fatty acids. Powdered Bladderwrack has been mixed with olive oil as a safe effective alternative to cod liver oil. Nori is very rich in vatamins A & C. Special Therapeutic Uses: Lower Respiratory Problems: Phycocolloid carageenan gel, boiled out of red algae, notably Irish Moss (Chondrus crispus), Grapestone (Gigartina spp.) and Iridea, is both partially digested and absorbed as small globular polymeric masses. This gel is effective long-term treatment for damaged lungs, particularly after pneumonia, smoking, emphysema, chronic bronchitis and possibly Mycoplasma and Chlamydia.

Lung Function:

Regular consumption of Hijiki and Sargassum, brown algae, seems to aid respiratory function, improving lung capacity and gas exchange efficiency.

Herpes Outbreak Relief:

The red alga, Dumontia, is dried, powdered, encapsulated, and used as a genital herpes suppressant. Sources for Dumontia are listed on the net under genital herpes. I discourage using Dumontia because of very limited amounts of wild plants. Prionitis Lyallii, a much more abundant tidepool red alga from California to Alaska, is used similarly. It has not been tested clinically or in any long-term treatment programs.

Shingles Outbreak Relief:

Three different red algae harvested in Southeast Alaska by R. Ellis and Natasha Calvin, are also dried, powdered and encapsulated and taken in prescribed dosages regularly to suppress outbreaks of Shingles, Herpes zoster. They are called Alaska Dulse together.

Erectile Dysfunction:

Tropical species of Gracilaria, an agarophyte red seaweed, are used to prepare a male virility drink variously called Seaweed Drink or Sea Moss Tea in the Caribbean.There seems to be improvement in both desire and performance. Local demand was sufficient to foster nearly total elimination of these seaweeds on many islands. The drink is prepared similarly to the respiratory gel described above, namely, by repeatedly boiling the same algal mass until no more gel remains. I tried the drink on Caye Caulker several times and concur that desire for coital intimacy seemed to be enhanced.

Tissue Repair:

I use a broth of powdered Sagassum muticum (a large local brown alga) and unpasteurized 3 year old Barley Miso paste for all cancer. radiation, chemo, post-surgical, and wholebody impact trauma (acute auto crashes, falls) patients. I recommend twice daily, AM and PM, mixing 15 ml of miso paste with 5 gm of Sagassum powder in about 300 ml of hot (120 F) non-chlorinated water. For cancer patients I also recommend 15 ml fresh pressed sheep sorrel (Rumex acetosella) juice from live plants twice daily with food. For trauma patients I recommend 20-40 Hawthorn berries (Crataegus oxycantha or C. monogyna) or 5 ml Hawthorn Tincture three times daily with food. Japanese studies show very positive clinical and preventative anti-tumor, anti-metastatic success using seaweeds, especially Sargassum.

Nervous Disorders:

Attention Deficit Disorder (ADD), Hyperactivity, Insomnia, Depression, Hostility and Schizophrenia are often markedly improved if not resolved by regular consumption daily of 3-5 gm powdered kelp, especially Bull Kelp (Nereocystis). I assume here we are treating basic long-term malnutrition, especially mineral deficiency. Hay Fever and Asthma are also helped by 3-5 gm powdered kelp daily.

Bladderwrack:

Bladderwrack (Fucus spp.) has many therapeutic uses. I find the best results develop when small pieces of the whole plant are eaten with food; next best way is ingestion of encapsulated powdered dried Bladderwrack; alcohol and hot water extracts seem to be the least effective. Regular consumption of 3-5 gm daily can normalize a swollen prostate, especially in early stages. An external poultice or soaking in Bladderwrack baths, the hotter the better, can relieve sore joints and achy muscles; it may stimulate cartilage regrowth. Regular consumption of Bladderwrack can also lower chronic high blood pressure, promote healing, and improve sleep. Much of the iodine in bladderwrack presents as di-iodotyrosine(DIT) , an immediate precursor of the thyroid hormones Thyroxine (T4, made from two condensed DIT molecules by thyroid peroxidase in the thyroid follicles) and tri-iodothyronine (T3, made from the condensing of one DIT and one MIT).This makes Fucus spp the sea vegetables of choice for treating thyroid disorders by providing the immediate precursors for T4 and T3. Indeed, Fucus seems particularly effective in treating early stage hypothyroidism. Positive results have obtained in both hypothyroidism and Graves' hyperthyroidism cases.

Phytoestrogens:

Many seaweeds contain significant amounts of lignans which are readily converted by intestinal microflora to non-steroidal estrogenic molecules which bond preferentially to ErB, the recently discovered estrogen receptor site. There are often more lignans in selected seaweeds than in legumes, whole grains, vegetables and fruits.This may explain their apparent therapeutic and preventative value against estrogen-driven neoplasms.

Cardiac Troubles:

Regular consumption of Kombu (Laminaria spp.) tends to result in lowered blood pressure, plaque removal from arteries.

Breast Cancer:

Regular dietary consumption of Wakame and other brown algae may prevent breast cancer. Fucoidan:Fucoidan is a sulfated polysaccharide extracted from many brown algae with hot water. It is a potent antiviral; it can inhibit virus attachment onto host cells, inhibit cell penetration, and inhibit viral intracellular replication. It shows strong activity against Herpes Simplex 1 HIV 1 and H-Cytomeglovirus. It also inhibits lung metastases. It shows strong antitumor activity by enhancement of inflammatory responses and upregulation of leukocytic phagocytosis. It is more antiproliferative than comparable doses of Heparin. All human cells studied are found to have receptor sites for Fucose, the end-group sugar on Fucoidan.This molecule is perhaps most important in the therapeutic future for seaweeds. I hope that it will be given as whole seaweed powders rather than industrial extracts with their inevitable contaminants. Pretreatment with Fucoidan significantly reduces hemorrhagioc shock pooling increase in the vascular bed after surgery.

Research continues. Eat sea vegetables today!!!

Medicinal Uses of Seaweeds

INTRODUCTION

Seaweeds offer a wide range of therapeutic possibilities both internally and externally. The term Seaweeds in this case refers only to macrophytic marine algae, both wild and cultivated, growing in saltwater.

Botanically, seaweeds are classified as Green, Brown, or Red. A particular seaweed’s placement in one of these groups is determined first by its photosynthetic pigments, then its reproductive mode, then its micro and macro morphologies, and finally by its phycopolymers. The obvious visual color of a particular seaweed species may not match its taxonomic color, which can be confusing to the beginner. Persevere.

Here I will discuss seaweed’s primary and secondary metabolites and some of their respective peculiarities and therapeutic uses. References are provided for further information .

SEAWEED CONSUMPTION

Simply eating unprocessed dried seaweeds can yield many healing benefits. Many physical ailments in both humans and their companion animals can be regularly resolved with the simple addition of seaweeds to their respective diets. Although therapeutic seaweed constituents can be extracted singly or in clusters, in cases of chronic conditions, I usually recommend patients eat seaweeds, not extracts. I prefer the seaweeds to be eaten uncooked in most cases. The digestive flora in a particular person may take up to 4 months to agree to produce dedicated enzymes to thoroughly digest dietary seaweeds. Oftimes the individual’s enteroflora must commit resources to recognizing the molecular structures on and in seaweeds and subsequently use them as food. This is the basis for the recommendation that it is far more productive to eat a small amount of seaweed daily rather than larger amounts occasionally. The key to bacterial dietary adaptation is continual exposure to the new food material. Consequently, positive therapeutic changes caused by eating seaweeds regularly may take several weeks to several months to become obvious.

RESISITANCE TO EATING SEAWEEDS

When patients are oral adverse to the tastes, smells, and/or textures of seaweeds, I urge them to add seaweeds as small pieces or powder(s) to foods strongly flavoured with spices such as: cayenne, fried onions, raw garlic, chili powder, curry, or vinegar.

SEAWEEDS AS MEDICINE

Seaweeds as the Best Dietary Sources of Essential Minerals


All essential minerals are provided by dietary seaweeds. No land plant even remotely approaches seaweeds as sources of metabolically-required minerals(See Bergner1997). Seaweeds can provide minerals often absent from freshwater and food crops grown on mineral-depleted soils. In addition to eating seaweeds regularly, those gardening for food can use copious amounts of seaweeds for mulch and fertilizer(Traditional Irish fertilizer, see: Man of Aran, and The Field), add seaweeds abundantly to compost, and even make seaweed tea sprayed directly onto leaves for foliar feeding through the stomates , as ways to therapeutically get trace elements into patients a trifle covertly.

Leon Uris in his novel, Trinity, delightfully describes the social scene accompanying “kelping” by the Irish.

Seaweeds are 20-50% dry weight mineral(Kazutosi, 2002). This figure is obtained by burning off seaweed’s organic material and weighing the remaining ash. The elements abundant in seaweeds include: potassium, sodium, calcium, magnesium, zinc, copper, chloride, sulfur, phosphorous, vanadium, cobalt, manganese, selenium, bromine, iodine, arsenic, iron, and fluorine.

The large Brown seaweeds (Laminaria species ( known collectively as Kombu), various kelps(Icelandic kelp, Norwegian kelp, Bullwhip kelp,Sugar kelp,Giant Pacific kelp, and Hijiki), Bladderwrack, Rockweed, Sargassum, Wakame, and Sea Palm, tend to contain more minerals per unit weight than the Red seaweeds (Nori, Irish Moss, Dulse, Grapestone, and Euchemia).

Many human body substances require particular mineral elements as part(s) of their respective structure. Examples are iron for hemoglobin and iodine for thyroxine.

For our bodies to function, we use proteins called enzymes. Most enzymes require one or more coenzymatic factors; these coenzymatic factors are usually one or more metals. cations. Chronic dietary shortages or disease-related mineral depletions can produce both specific and general disease conditions: Iodine shortage results in varying degrees of thyroid dysfunction; poor absorption of dietary calcium can result in osteoporosis. Adequate residential body mineral supplies are critical for optimal body system functioning. My personal observations support the notion that non-specific disease categories such as Chronic Fatigue, lack of energy, subclinical depression and depressed immunity are probably due to inadequate minerals either in the diet and /or in the body. Many times I have seen chronically exhausted patients exhibit complete symptom resolution after several weeks of adding 5-10 grams of seaweeds to their daily diets.

In the hydrated seaweeds, raw or cooked, minerals are mostly in aqueous solution and readily available for intestinal absorption in humans. These accumulated minerals can be loosely considered primary metabolites. Even though they are not manufactured by the seaweeds, they are concentrated against the osmotic gradient to cause a much higher concentration of each mineral inside seaweed cells and intercellular spaces than in the surrounding seawater. This enables seaweeds to use water equilibrium mechanics to move materials in and out of their cells. It is no accident that seaweeds concentrate metal cations and other elements many times their respective concentrations in seawater. They have almost unlimited access to mineral resources unavailable to most land plants and animals.

CAUTION:

Celtic Sea Salt and other designer so-called natural or raw, evaporated seawater sea salt products are not good sources of some trace elements, particularly iodine, iron, copper, and selenium. This is unfortunate since just plain sea salt is basically healthier than the modified commercial table salts.

IODINE

The single most important element provided by seaweeds, is Iodine. It is more abundant in seaweeds, any seaweed, than any plants or animals. Land plants, vascular plants in particular, seem to have no detectable iodine requirement.

ALL vertebrate animals REQUIRE IODINE. This iodine is used in thyroid hormones, T4, thyroxine, and T3, tri-iodothyronine to control all fetal development, postnatal growth, and ongoing daily body metabolism. No iodine, no vertebrate life. The choice of iodine seems to have been its isoptopic stability: there is only one known natural iodine isotope, iodine 127. It is reliable, not subject to radioactive decay.

When vertebrates lived in the sea, even at about 60ppb, there was a constant reliable source of iodine. Since some vertebrates left the sea, obtaining enough iodine has been a challenge to their descendants, including ourselves.

Since no land plants have a need for iodine, their taking it in from roots or leaves may be just incidental. That has meant that few land plants are reliable or even adequate iodine sources unless consumed in large quantities as by large herbivores. Plants grown proximal to the marine environment and those deliberately fertilized with seaweeds can accumulate enough iodine to provide adequate dietary supplies for herbivores and humans. Potatoes, garlic and other root crops are the best accumulators and dietary sources of plant-based iodine supplies.

Eating 3-5 grams of most dried, unrinsed seaweeds will provide the RDA of 100-150 micrograms.

Lack of iodine can cause developmental structural and neural fetal abnormalities collectively called cretinism. This condition, directly as a result of low maternal iodine supplies, is difficult to correct postpartum, if at all. The treatment is adequate maternal iodine consumption from the mother’s initial beginning as an egg in her maternal grandmother.

That means treating the problem 2 generations before a particular pregnancy. In the moment, maternal iodine supplies can be monitored by maternal urine testing and any deficiencies immediately corrected by adding dietary iodine. Mammalian fetal iodine need is about three times per unit body weight of the mother.

In adult humans, chronic low iodine consumption often results from iodine deficient soils and water, and consequently low iodine food. The human consequence is: first, goiter, an enlargement of the thyroid gland, deliberately generated by TSH (thyroid-stimulating Hormone) to increase thyroid gland cell surface area and more “iodine traps”,and secondly, various manifestations of hypothyroidism.

The treatment is often simply more dietary iodine for both conditions And this can be easily accomplished with dietary seaweeds.

Chronic pernicious human iodine deficiency developed during 7000 of continuous extractive agriculture in the interior of China resulting in tens of millions of near-cretinous citizens by the mid-1900’s. For treatment,the Chinese developed warm-water Laminaria kelp varieties which they now cultivate in great quantity with entire villages growing and processing up to 650,000 metric tons each year to provide more than enough dietary iodine for 1.5 billion Chinese(Druehl,2000). This is a most curious successful marvel; nearly 5000 years ago, in an herbal attributed to the Emperor Shen Nung, goiter was described, and the treatment was seaweed, apparently Fucus. Nori seaweed was also touted as the most wonderful elixer (Katzutosi).

CAUTION:

Some individuals are extremely sensitive to iodine. A little bit too much intheir diets and they begin to exhibit hyperthyroid signs and symptoms: nervousness, heart palpitations, sleeplessness, irritability and even iodine-induced goiter. If these symptoms appear, first inquire about seaweed/iodine consumption(from any source, including dairy and baked goods). Individuals with “seafood allergy” seem especially sensitive to iodine. Contrary to some practitioners and their believing patients, nobody has “iodine allergy”. No iodine, no life.

SEAWEED IODINE CONTENT

Icelandic kelp, 8000ppm, Norwegian kelp 4000ppm, Atlantic kelp 1500-2000ppm, Pacific kelps 500-1200ppm, Fucus spp. 200-500ppm, Wakame 50-150ppm, Sargassum 35ppm, and Nori 15 ppm. These are all approximate and will vary considerably by season, location, age, and harvest practices.

The Japanese and other Asians apparently usually soak their Kombu and other seaweeds in freshwater for 10-30 minutes prior to using in miso broth and other cooking , which removes about 60% of the iodine (Hazutosi). Curiously, I was told by Japanese nationals that the kombu was left in the miso broth for 10-20 minutes and then discarded.

The soaking or prolonged rinsing of high-iodine content seaweeds may reduce the risks for excess iodine-induced disease.

For some interesting views on iodine and health, please see Guy Abraham MD’s website, www.optimox.com

IODINE PROTECTION

The iodine story as related to human health took an interesting turn when Uranium was used to cause nuclear fission: one of the decay products of nuclear explosions is Iodine 131. That means not only nuclear weapons, bombs, but also, all of the controlled nuclear events in Nuclear reactor fuel rods. ALL NUCLEAR FACILITIES release radioactive Iodine 131 into the atmosphere. Hundreds of them are licensed to do so. This means that we are all continually and erratically dusted with Iodine 131 every day of every year. As shown by reliable research for over 50 years, nuclear power plant stack gases circle the earth in 3-5 days, continuously dusting us all until all settled. Additionally, there are nuclear disasters, such as Three-mile Island in USA and Chernobyl in Ukraine. The Chernobyl disaster on 26.April 1986 released enormous quantities of Iodine 131 into the atmosphere. Since then, millions of iodine131-induced thyroid disease patients have been reported worldwide starting shortly after the event and continuing today. Relatively rare 20 years ago and unknown prior to 1945, thyroid cancer is now the number one cancer in children in USA. Thyroid cancer is one of the fastest increasing cancers in both adult men and women.

Iodine 131 is hazardous because our bodies will happily take it in if we need iodine. Since prior to the human atomic age there was no iodine 131, we have no defense against it if we need iodine, and no way to selectively excrete it. IF we have sufficient iodine in our bodies, Iodine 127, the only natural iodine isotope, our bodies will not take in the heavier iodine 131. How the weighing is done is an interesting question to be considered elsewhere. The critical information is: if we continually take in 150 micrograms of iodine 127 daily, we will most likely be protected from iodine-deficiency “iodine aggressive uptake”. We can do this by eating 5-10 grams of seaweeds daily. If we are worried about iodine 131 which reasonably might be expected in the seaweed, we can let the seaweed iodine 131 if any, decay for 8 weeks. How do we know and expect this seaweed iodine to be protective against iodine 131 fallout and decay? The Polish example. Within hours after the onset of the Chernobyl disaster, Polish authorities acted to get iodine solutions, potassium and sodium iodide tablets, even seaweed tablets and capsules into as many of their citizens as possible to protect them from the nearby huge amounts of iodine 131 coming their way. Over the intervening 20 years, the Polish people treated with iodine 127 have almost 1000 time less thyroid disease than neighboring countries even further than Poland from the Chernobyl disaster site.

Unfortunately, ALL Nuclear Power Plants are nuclear disasters waiting to happen. Not because of evil intent (we hope) but because of mechanical and materials deterioration and human error. Hundreds more nuclear power plants are planned, especially by developing countries anxious to reduce their energy dependencies on fossil fuels. Of course, that will mean increasingly huge amounts of radioactive iodine 131 into the atmosphere and huge quantities of nuclear waste begging for safe disposal. Simpler of course, would be to boil water with solar mirrors. All nuclear power plants so far are just fancy water boilers. Strange.

Eat your seaweeds.

Iodine passes readily through the epidermis, and alveolar cell walls into the body in addition to intestinal absorption. This means that any iodine 13l we breath or get on our skins is likely to be absorbed if we are the least bit iodine 127 deficient.

How is iodine 131 hazardous? It radioactively decays with a half life of about 8 days. This means in 8 weeks, there is probably not much left in a particular sample, and not enough to cause radiation damage. Iodine 131 decays with the release of a high energy Beta particle, which crashes ionizingly through adjacent tissues, and ionizing high energy gamma radiation. There is no safe exposure to radioactive-decay sourced ionizing radiation (Shannon, 1995)

POTASSIUM

All living cells, and that means all of our cells, need potassium all of the time to function and stay alive. There are no exceptions. Our bodies have no innate potassium conservation mechanisms. The human evolutionary assumption seems to be that we will always have plenty of potassium available in our wild and live food diets, since all living cells require potassium. This is in contrast to sodium, also an essential element, for which we have a very rigorous sodium conservation mechanism.

The human tongue, just as the average beginning analytical chemistry student, seems to have difficulty distinguishing potassium from sodium: both taste salty. In equal amounts, potassium is up to 8 times saltier than sodium.

Often, overwrought patients will complain of constant “salt cravings” even though they eat a lot of salty foods.”I just can’t seem to get enough salt” is a common statement. These people are often overweight, puffy (edemic), and complain of exhaustion. I suggest high-potassium powdered seaweed (almost any seaweed, although the kelps tend to have more potassium than other seaweeds) up to 10 grams daily until symptoms resolve. So far, I have not encountered any indications of potassium toxicity which might have been caused by excessive consumption of hi-potassium seaweeds, although such poisoning may be possible. If practitioners are concerned, prescribe less seaweed consumption at any one time.

I believe that almost any craving for salt in our dietary times of heavily salted, with sodium chloride, home-cooking, restaurant meals, and preserved foods is a strong indication of potassium deficiency, especially in pregnancy.

Potassium is essential for even minimal nerve and muscle functioning, and as a cross-membrane transporter ion for neurotransmittors and hormones. I have observed that adding high-potassium foods, especially seaweeds, to the diets of ADD children (instead of Ritalin) and adults can significantly improve behavior and mental functioning.

Similarly, fibromyalgia patients, the exhausted, the forgetful, the moody, the agitated, anxiety disorders, and depression are all favorably improved with high-potassium diets and seaweeds.

YES! Before grabbing the herbal nerviness and muscle analgesics, try feeding the nerves and muscles their essential mineral foods: potassium, sodium, calcium and magnesium The last three, are all abundant in all seaweeds: sodium,2-4%, calcium 0.5-1.0%, magnesium 0.2-1.0%.. In addition to optimal nerve and muscle functioning, these four elements are important in transporting many substances along the intercellular integrin network.

Many women patients eating seaweeds to reduce PMS symptom severity report a distinct cyclical waxing and waning of seaweed cravings.

SELENIUM

Selenium is present in all seaweeds in physiologically significant amounts.

Selenium is, like its partner in thyroid hormone metabolism, apparently not required by any land plants although some do concentrate it (Brazil nuts are the usual culprit). No selenium, no thyroid hormone production and conversion of T4 to T3.

Selenium is present in all edible animals, and is easily absorbed from eggs in the diet. Selenium is required for many critical metabolic actions besides the selenodeiodinases.

Men usually have a much higher selenium demand than women because, like zinc, it is secreted in the male reproductive ejaculate, and must be replaced to maintain ejaculate production and sperm fertility. Check for selenium deficiency in males with fertility issues.

PHYCOPOLYMERS

All seaweeds contain a large proportion (25-40%) of mucopolysaccharides , collectively referred to as Phycopolymers.

The brown algal phycopolymers are algin and fucoidan, both sulfated galactans.

ALGIN

Algin has great therapeutic value as a heavy metal detoxifying agent.. When added to the diet as a component of edible brown seaweed, algin powder, or sodium alginate, it can bind heavy metals present in the food stream and carry them out with the stool, since algin is generally not digestible(Schecter.1997).

Excretory algin tends to bind metal ions presented in the small intestine from distal body locations. A complex diffusion gradient transport system will move poisonous metal atoms a few at a time to the intestine for probable binding to insoluble dietary fiber. Apparently this is a way of removing hazardous metals in a way which avoids damaging the kidneys. Regular eating of even small amounts of brown algae can be an ongoing metal detoxification practice which can reduce the quenching of enzymes by heavy metals.

Hair analysis can be a better predictor of excess metal poisoning than blood or urine analysis because the body seems to use the sulfhydral groups in hair proteins as an excretory mechanism which also protects the kidneys. If a patient presents with relatively high levels of toxic metals in hair, blood, or urine, the addition of 3-5 grams brown seaweed to the daily diet will help remove those metals from the body, but not the hair, of course.

Using brown algae as part of an aggressive metal removal treatment plan is recommended for both acute and chronic exposures and actual poisoning. Reducing further exposure to heavy metals is of course essential for a metal removal plan to succeed. I usually recommend a lot of rolled oats in the diet ( every morning) to aid the seaweeds in metal removal. For some persons, adding the seaweed to the oatmeal seems to hasten metal removal. This combination will tend to bulk the stool and reduce transit time. I also encourage at least 2L of water (just water, not drinks) intake daily; as well as frequent hot baths and saunas with vigorous dry skin brushing before and after each bath or sauna.

Chronic Passive Metal Poisoning

Industrial activities, mining, and nuclear power activities release relatively large amounts of usually unseen toxic metals into our air, water, and unfortunately onto our food crops. We are all being continually poisoned.

From nuclear facilities (radioactive medical wastes are increasingly a source of radioactive metal poisoning) we are exposed to radioactive isotopes released into the air by way of gaseous emissions and radioactive substances released into cooling water.

Since most of these exposures are probably going to continue for the foreseeable future, we are advised to do what we can to reduce their negative health effects. The best action may be to eat a diet that is continually detoxifying our bodies. Regular seaweed consumption should be a part of that diet.

I predict that age-related dementia and perhaps Alzheimer’s can be prevented or suppressed by regular consumption of algin-rich brown seaweeds, to slow the bioaccumulation of neurotoxic metals. The kelps and popular dietary brown seaweeds can do this.

Some of the salts of alginic acid present in aqueous solutions in ingested brown algae, such as potassium and sodium alginates, are digestible by intestinal flora. The metals they contain are released into the food stream and tend to be bound up by the undigested algal fibers.

FUCOIDAN

Fucoidan can be easily cooked out of most edible brown algae by simmering 20-40 minutes in water (alone or in food). When consumed, it seems to reduce the intensity of the inflammatory response and promote more rapid tissue healing after wound trauma and surgical trauma. This means that brown seaweed broth is recommended after auto collision , sports injuries, bruising falls, muscle and joint damage, and deep tissue cuts, including voluntary surgery.

Surgery

I recommend patients anticipating surgery eat 3-5 grams brown seaweed cooked as a vegetable broth daily for a week or two prior to surgery. Fucoidan in the pre-surgical patient diet seems to reduce the intensity of blood loss and vascular bed collapse shock during and after surgery. The mechanism for this positive effect is unclear.

We can all statistically expect major surgery sometime in our individual lives. We are the only animal that voluntarily submits to surgery. I believe this may cause some body integrity sanctity problems internally which may negatively effect the wound response and subsequent healing. Fucoidan may help the body decide to heal after voluntary surgery and other wounding such as radiation and chemotherapy.

Patients undergoing radiation or chemotherapy seem to benefit from regular fucoidan consumption via brown seaweed broth before, during, and after treatments. They report fewer and less intense adverse reactions, better recovery and sense of well-being.

Antiviral Action

Fucoidan interferes with every stage of viral attack, cell attachment, cell penetration, and intracellular virion production by stimulating the production of antiviral cytokines. There may be some viral suppression in virus-infested patients but results are difficult to verify or measure. Research continues into using fucoidan or its derivatives to combat common viral infestations: HIV, HPV, and Herpes.

A fucoidan curiosity is that its teminal sugar is Fucose. All human cells studied have very precise Fucose recepter sites on their surfaces. Perhaps this results in stronger therapeutic responses.

RED ALGAL POLYMERS

The main red algal polymers are agar and carrageenan, and mainly porphyran in nori. All of these polymers are sulfated galactans. They are modestly water-soluble, partially digestible and easily extracted from red seaweeds by boiling .

Carrageenan

Carrageenan was originally isolated by simply boiling red seaweeds for an hour or more , discarding the seaweed mass, and saving the usually thick mucilaginous liquid. It was used for soups, hot gruels when mixed with grains, seafood, and peas. It was drunk as a soothing treatment for sore mouths and throats and for constipation relief.

It was used by the poor starving Irish during the oppressive British occupation of Ireland for 800 years as an emergency food, filling if not totally nutritious.

Today, carrageenan is used in over ten thousand proprietary industrial, food, and health and beauty products as a thickener, gelling agent, meat and sugar extender, medicines, and paints. Red seaweeds containing carrageenan have been overharvested in many places, including the intertidal zones of the Canadian Maritime Provinces and many of the Carribean Islands. Now, to meet demand, the world’s largest aquaculture farms are located in Malaysia, Indonesia, and the Philipines, where the red alga Euchemia is grown on nets. Historically, it has been used as a sexual lubricant in China, Korea, and Japan for millennia.

Carrageenan eaten as red seaweeds such as dulse, Irish moss, and Euchemia, is partially digested and absorbed as small globular gel masses into the lymph and blood stream. It can provide sugar molecules for glycoproteins secreted by mucous membranes and for cell surface aminoglycan labeling.

Medicinal Uses

RESPIRATORY TREATMENT

Until 1935, pneumonia was the leading recorded cause human death in the USA. 100 years ago, five of the top ten causes of death in men were respiratory diseases.

Today, asthma is the leading cause of juvenile school absenteeism and is increasingly an affliction of adults.

Red algae containing carrageenan have been used for millennia as treatments for respiratory ailments, especially intractable sinus infections and lingering pneumonias. Asthma was not separated out as such in the old literature.

I use plain boiled- out carrageenan singly or in combination with strong antimicrobial herbs for all respiratory ailments.
The process is simple:
Place an ounce of carrageenan-containing red seaweed in a food-grade mesh bag
Place the bag in a stainless steel boiler or ceramic “Crockpot” containing up to 1l of water.
Bring to a boil and simmer for ½-4 hours. The bag of seaweed can be left in the crockpot, setting at LOW, for 8-12 hours, which means overnight for breakfast readiness.
Stir or otherwise pump the gel out of the mesh bag while simmering; this will move the dissolved gel out of the bag and allow more extraction. If this step is omitted, the gel may just thicken , clog the mesh pores, and remain a mess in the mesh bag
Pour off the fluid gel, while hot
If only one extraction is enough, hang the bag from something over a container and let more gel drip out
The red seaweed mass remaining in the mesh bag can be simmered and the gel fluid poured off again and again, up to 4-5 times with more gel extracted each time
The gel can be consumed as soon as cool. It can be flavoured with anything suitable from honey, fruit juice, cinnamon, cayenne, vanilla, maple syrup, cocoa powder, to various distilled spirits, herbal tinctures and milk.

The extracted gel will keep cold without spoiling for only about two days. It is an excellent growth medium for microbes. Do not leave gel unused for more than two days in a refrigerator with out boiling again briefly to sterilize it.

I recommend consuming at least a pint a day for children and a quart or more per day for adults up to a week or until respiratory symptoms resolve.

In cases of obvious microbial infection, add strong herbs such as elecampange, osha, Lomatium, even garlic in the extraction bag, or as a separately-prepared tea mixture; tinctures can also be added to the gel after removing from boiler.

The herbal-enhanced gels are usually good expectorants and can improve cough productivity.

The first gel extracted is often very strongly seaweed- flavoured and unpalatable to children and those with a resistant sensitive nature. The flavourings listed above can mask the strong seaweed flavours.

Those flavours are usually not present in the gel produced in second and more extraction episodes of the same bag of red seaweed.

I think that cases of respiratory mycoplasma (often presenting as adult-onset asthma in people over 35) are helped by the gel with the addition of strong herbs, especially elecampagne.

A soothing carrageenan gel variant is to use 5 parts red seaweed, and one part each : Usnea lichen, fennel seeds, marshmallow root (powdered) and hawthorn berries. This is very helpful for throats sore from excessive coughing.

CAUTIONS for Red Seaweed Gel Use: Small amounts of carrageenan gel can help heal ulcers including ulcerative colitis. Large amounts may worsen alimentary ulcers and erosive bowel diseases, especially in the bowel if carrageenan successfully competes with the bowel membranes for water from the stool.

ANTIVIRAL RED SEAWEEDS

In vitro tests in the 1950’s and 1960’s showed that some red algae are strongly antiviral. The ideas were developed by Robert Ellis and Natasha Calvin, who used scuba gear in SE Alaska to harvest three species of subtidal red algae to produce a mixture called Alaska Dulse. This was taken internally as a very effective treatment for SHINGLES.

Natasha has passed and Robert is no longer providing the Alaska Dulse. From Blue Moon Marine, Kim and Mark Donovan are test-marketing antiherpetic crèmes and lotions for cold sores, shingles and hopefully genital herpes. I have tried their products on recurring shingles with some lessening of lesion severity but not a great improvement. Clinical trials are underway in cooperation with the Bastyr University Clinic.

Strong antiviral activity has been observed in a variety of heavily modified carrageenans and research continues on how to use this in commercial medications. I do not know if occasional consumption of red seaweed gels will be antiviral.

One carrageenan derivative showed strong anti-HIV activity when delivered as a contraceptive vaginal foam.

ERECTILE DYSFUNCTION

On a very memorable visit to Caye Caulker in the Belizian Carribean, I had an interesting seaweed encounter. Whilst strolling along the unpaved path of the merchantile zone, we came upon a little juice stand where fresh tropical juices were made and sold. The children were thirsty as usual and so we got some watermelon banana pineapple slurries for them. I noticed a couple of recycled whiskey bottles with hand-printed tape labels that read “SEAWEED DRINK”. I inquired about it. It was the most expensive item on display. The young woman in charge said she did not know much about its manufacture, but I could talk with the owner tomorrow at a time designated. I bought a bottle and she recommended that I flavour it with rum or whiskey, since it did not have any alcohol in it and it would spoil quickly in the tropical heat. “It make you strong, mon!” she assured me with a BIG smile.

I did not add any alcohol and drank it over an hour or two. It tasted just like red seaweed gel at home onisland. It took several days before I was able to meet with the owner and seaweed drink maker. He was extremely reluctant to talk about the product. Eventually I told him about my own production of seaweed drinks back in Washington State and he eased up a bit.

He told me that the process had been the same for thousands of years, used by the Ancient Maya and the Arawaks and Caribs. Using stone-weighted poles with hooks, the seaweed was spun off the seafloor and loaded into canoes or now small sailboats and brought to shore where it was laid out in the sun to be washed by rains and bleached by sun until a yellowishwhite colour and no seaweedy flavours remained. The mass looked like distressed pasta noodles when he gave me a big handful of dried seaweed. He told me that just like grapestone, it could be boiled many times and thick gel came out each time, up to 12 times. Impressive. He was especially reluctant to take me out to witness the harvest or do some myself. The Rastafarians had the Seaweed Drink monopoly and perhaps he feared my setting up a little drink stand.

I bought several bottles of it during three weeks on Caye Caulker. Eventually the salespeople asked “How you doin, mon?” I had to be educated as to the intended purpose of the Seaweed Drink. It was a renowned local treatment for erectile dysfunction and my otherwise recreational excessive purchases and assumed consumption was cause for much laughter and smirking stares.

I really could not detect any positive therapeutic effect or behavioural changes.

Eight years later I get an inquiry from some patients who are looking for Sea Moss. I checked in with some of my phycological colleagues, notably Dr. Mel Goldstein of U. Victoria in BC.

He had been in charge of the Sea Moss recovery program in Santa Lucia, Virgin Islands.The popularity of Sea Moss as a virility drink had led to its extermination from all of the larger Carribean islands and locals were continually asking him during his research years there, where he had seen any Sea Moss It was very rare and occurred only on tiny dangerous uninhabited rocky islands He decided to try and use basic seaweed mariculture techniques to grow Sea Moss using starts from wild patches. It worked eventually and many bays on the Virgin Islands, Jamaica, Barbados, Trinidad, and other islands have ropes and poles growing Sea Moss to meet an expanding market demand. The red seaweeds , species of Euchemia, Gracillaria and Hydroputia were originally harvested to make a traditional pre-contact breakfast gruel, and to thicken jellies as well as make soothing drinks. Now, Sea Moss is sold in tourist shops , featured in local jams and jellies, and served as a special ethnic gruel to tourists.

The Maya apparently used the gel with ground cacao, vanilla bean, and honey to make a treat.

I have no information about erectile dysfunction amongst the ancient Maya.

I make the assumption that the Sea Moss drink must have had some positive effects on male libido or erectile dysfunction. What the actual effects in terms of tissue changes might be, I can only speculate that circulation may be improved and mucous membranes more productive. There are many causes of erectile dysfunction and most of these are behavioral, such as smoking, alcohol consumption, chronic dehydration, obesity, medications, sociology. I doubt if seaweed drink alone will overcome these causes. We will keep trying, however.

HORMONES IN SEAWEEDS

Melatonin

Melatonin is abundant in many seaweeds, up to 1000 times the amounts found in land plants such as Feverfew and St. John’s Wort. This may explain some of the calming effects of eating seaweeds. Night-time harvested seaweed has much more melatonin content than daytime-harvested seaweed of the same species. There may be some useful therapeutic opportunities using seaweed-sourced melatonin.

Thyroid Hormones in Seaweeds

Brown seaweeds are the only known non-animal sources of thyroid hormones.

The presence of organically-bound iodine in brown seaweeds as thyroid hormones may explain some of the effects of eating some brown seaweeds.

DI-IODOTHYRONINE (DIT)

Fucus spp of brown seaweeds have been used as treatment for thyroid disorders . The thyroid hormone present in Fucus is Di-Iodothyronine (DIT); it is weakly active if al all as a thyroid hormone in the mammalian body. Two DIT molecules are condensed in an elegant esterification reaction to produce tetraiodotyrosine(T4, Thyroxine). The organically bound iodine in Fucus may enhance T4 production by providing some prefabricated portions of T4. I have not seen any studies tracing Fucus-sourced DIT to either the thyroid gland or circulating T4.

The therapeutic effects of using powdered Fucus, 3-5 grams daily resemble the therapeutic effects of thyroxine medications: shrinking of goiters, weight loss, resolution of symptomatic non-autoimmune hypothyroidism, return of vim and vigor, lessening of psychiatric disruptions, and resolution of eczemas. This is especially true of women enduring postpartum physiological depression after several years of being pregnant and nursing one or more children.

I have seen no reports of thyrotoxicity from Fucus consumption.

Women with low thyroid function, according to thyroid panel blood tests report improved test results.

Any similar results from using Fucus teas will be due to inorganic iodine supply increase and probably not from DIT. DIT is not very water soluble.

Fucus is used to wean mildly hypothyroid patients off thyroid hormone medication.

This can work only if the patient has a thyroid gland mass capable of making T4 and T3 in sufficient quantities to supply body needs. Those without a thyroid gland may be helped by the iodine from Fucus, alleviating the need to mine thyroid medications for iodine. This may also explain in part the alleged weight loss results from ingesting Fucus; to wit, upregulation of basal body metabolic rate from iodine alone.

Thyroxine and Tri-iodothyronine in Brown Seaweeds

T4 and T3 have been found as the main organically bound iodine compounds in several brown seaweeds, notably Laminaria sp. and Sargassum sp. Up to 10% of Lamiarian iodine may be in MIT, DIT, T3, orT4. Even more in the less commoinly available Sargassum (less commercially available; it is a rapidly expanding invasive of all temperate coasts; this may be good news for thyroid sufferers) (Kazutosi 2002).

Kombu is one of the top 5 most consumed seaweeds in Japan and USA. The physiological effects of regular kombu consumption can be: resolution of coronary artery disease, healthier liver function, higher metabolic rate, faster food transit time, lower LDL cholesterol,, higher HDL cholesterol blood levels. If the thyroid hormones in kombu and Sargassum are available from food, this could turn out to be an effective treatment to replace both synthetic thyroxines and animal-thyroid medications.

I assume at least some T4 and T3 get into the human body from dietary Kombu and stimulate more rapid clearing of fatty wastes from the liver, enabling more rapid removal of blood borne fatty wastes.

T4 and T3 are biphenols and are not water soluble. Oil extractions of Kombu may provide T4 and T3 as well as DIT and MIT(Mono-iodotyrosine) and be an effective thyrosupportive medicine.

Powdered Fucus is mixed with olive oil as a vegan replacement for cod liver oil and seems to work as well or better than cod liver oil

ESSENTIAL FAT AND VITAMINS IN SEAWEEDS

Most seaweeds are rich in vitamins, especially the B vitamins, including B12.

They also have significant amounts (1-3%)of Omega-3 fatty acids. Nori, in particular has 3% omega-3 fatty acids and large amounts of vitamins A and C. Interestingly, eating lots of nori is the Japanese prescription for boys who may have inherited male pattern baldness. In Scandinavia, the eating of refined sugars is discouraged for the same condition. Perhaps a combination could treat both hair loss and slow the progression of pattern baldness in both men and women?

BROWN SEAWEED- ENHANCED EXCRETION OF DIOXINS AND PCBS

Very exciting and encouraging research by Morita and Nakano (2) using seaweeds for Dioxin and PCB (polychlorinated biphenyl) excretion demonstrates clearly that the brown seaweeds Hiziki, Wakame, and Kombu speed body clearing of dioxins and PCBs.

Dioxins and PCBs are extremely toxic. They are lipophilic and are not water-soluble; they are readily absorbed from the digestive tract and stored in adipose tissue and the liver in abundance. Once stored, their eventual excretion tends to be very slow. Studies on Vietnam veterans and herbicide-spraying personnel showed dioxin body half-lives of 11.3-19.6 years.

In the excretory process, dioxins are shed from the GI walls into the food stream and expelled via the feces; but, only if they are not reabsorbed from the colon prior to actual excretion. It is this reabsorption that causes the prolonged body retention of Dioxins and PCBs.

The authors used rats in their initial seaweed experiments and monotypic encapsulated dried seaweed powders. Their results showed conclusively that:

Dietary seaweeds effectively inhibit reabsorption of Dioxin mixture congeners excreted into the gut from the GI walls and promote their fecal excretion.
The seaweeds inhibited the initial uptake of dietary-sourced Dioxins and PCBs from food, binding them for fecal elimination. Foods are the primary sources of Dioxins and PCBs for most of us.
Seaweeds accelerated whole body elimination of Dioxins and their metabolites.
Body processing of stored Dioxins before metabolite excretion was assumed to be hastened.
Although rat and human digestive physiologies differ, Morita and Nakano’s work strongly suggests that in humans regular dietary consumption of commercially available brown seaweeds will likely reduce Dioxin and PCB uptake and speed the fecal elimination of body-accumulated Dioxins and PCBs. The authors intend to use human subjects for equivalent research to demonstrate seaweed-enhanced dioxin and PCB excretion.

In the work cited, the most effective brown seaweed was Wakame, followed closely by both Hiziki and Kombu.

Dioxins, PCBs, and PBDEs (polybromated diethyl ethers) are found in all humans tested (100%)! This means that all of us can likely begin to benefit immediately from regular eating of 5-10 gm/daily of brown seaweed which can serve as toxic Dioxin, PCB, and PBDE exit vectors.

POST TRAUMATIC STRESS SYNDROME

I wonder about the probable relation of brain-loaded Dioxin and PCBs to psychiatric symptoms of Post Traumatic Stress Syndrome, especially considering the long body half-lives of these substances in adipose tissues. Since the brain is nearly 50% fat, it can be considered an adipose tissue.

In practice I would definitely recommend daily consumption of 4-10 gm Wakame and other dietary brown seaweeds for prevention of Dioxin and PCB uptake and their continual removal, bound to seaweed fiber, and excreted in the stool.

This work adds to the knowledge that regular consumption of brown seaweeds facilitates and hastens the removal of toxic heavy metals from both the human body and our ingested food. In addition to providing most of our essential mineral cations, brown seaweeds also rid us of dangerous health-negative substances.

THYROID HEALTH

PCBs and PBDEs are known endocrine and thyroid disrupters. In light of the toxin-removal results reported by Morita and Nakano, part of the thyrosupportive action of dietary brown seaweeds probably results from reducing PCB and PBDE uptake from food and their concomitant accelerated fecal excretion. This is in addition to providing thyroessential iodine (5) and thyroid hormone homologs (T4, T3, DIT & MIT), (l0).

WEIGHT LOSS

Those dieting for weight loss release adipose-sequestered PBCs, Dioxins, and PBDEs into their blood and lymph. Ingesting brown seaweeds may mitigate the negative consequences caused by weight loss toxin releases.

CARRAGEENAN INHIBITION OF PAPILLOMA VIRUS INFECTION

Papilloma viruses infect vertebrate skin and mucosal tissues. Human infection with genital HPV (human papilloma virus) is very common with an estimated lifetime risk of infection at about 75%. Most genital HPV infections are sub-clinical and self-limiting, but some persistently infected individuals have lesions that progress to cancer. Certain sexually transmitted HPV are allegedly responsible for most, if not all, cases of uterine cervical cancer, benign genital warts (condyloma accuminata), and a large portion of ano-genital cancer, and head and neck cancers. HPV-initiated cervical cancer is allegedly the #1 lethal cancer amongst women worldwide.

In 2007, the first prophylactic HPV vaccines were released. Their protection timeline for a vaccinated individual is unknown. The vaccines are recommended only for young women, 11-25 and are intended to be effective against only 2 of the at least 33 forms of genital HPV. They are expensive. Why are young men not being vaccinated, since they can carry the two suspected carcinogenic HPV strains? Will the next vaccine(s) protect against HPV-induced penile cancers?

In a bizarre instance of medical tyranny, the governor of Texas decreed that all young women, 11-25 were required to be vaccinated with the new HPV vaccines. Although described as a public health gesture, I suspect the real reason was to help the marketers recover their development costs at the possible expense of the young women being vaccinated. I applaud the sagacity of the Texas lawmakers who overwhelmingly voted out the decree.

In a rigorous study (3), Buck and colleagues, brilliantly demonstrate that carrageenan extracted from red seaweed inhibits HPV infection. The modified carrageenan (C-iota) acts primarily by preventing binding of HPV virions to cell surfaces; carrageenan also exhibits a post-attachment inhibitory effect on virions, quenching infectivity.

The research used tissue cultures and tissue models to test the carrageenan.

Carrageenan is an easily extracted, sulfated unbranched polygalactose red algal polymer. It is used in thousands of patented applications in food and cosmetic products and in sexual lubricants.

Carrageenan-containing sexual lubricants and condoms lubricated with gel containing carrageenan were extremely effective at blocking HPV infectivity, even when the condom gel was diluted one million times. The authors tested several condoms and sexual lubricants for HPV infectivity inhibition. Only products containing Carrageenan were HPV inhibitive.

Lubricants containing other seaweed gels, agar and algin, were much less effective HPV inhibitors. Non-carrageenan-coated condoms are, at best, only marginally effective for preventing sexual transmission of HPV.

Carrageenan in condom gels seems well tolerated by the human vagina. The pH of the human vagina is typically below 4.5. Carrageenan extracts maintain anti-HPV infectivity at pH 4.5.

I believe that carrageenan red seaweed extract gels are effective, relatively inexpensive protection against the spread/acquisition of genital HPV. There are no data yet about the real or potential treatment with carrageenan of existing HPV lesions. Seaweed gels have been used as sexual lubricants for 5000 years (5,11). Perhaps the antiviral prophylactic action of red seaweed gel as a microbiocide was recognized then. Carrageenan gel as a sexual lubricant is completely edible and a tissue stimulant. I suggest it should be investigated as a replacement for topical estradiol vaginal creams.

JORRP

A rare (1/25,000 births) HPV condition is JORRP (Juvenile Onset Recurrent Respiratory Papillomatosis), in which HPV-induced large benign tumors develop on airway surfaces. The main treatment is surgical removal of recurring obstructive masses. JORRP is thought to be vertically transmitted HPV types 6 or 11 from genital warts during birth. Pharmaceutical grade carrageenan gels could become a safe perinatal cervicovaginal preventative for JORRP and asymptomatic vertically transmitted HPV by adding the gels to the perinatal birth canal in women known to carry HPV types 6 & 11.

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Seaweed, thyroid, hypothyroidism, hyperthyroidism Cont'd
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